منابع مشابه
Childhood leukaemia Genetics and Ionising Radiation
The list of chromosome changes and gene mutations in leukaemia is now very extensive, involving more than 100 identified genes and including changes that are leukaemia subtype specific (Mullighan 2007, Han 2010, Oh 2010, de Jesus Marques-Salles 2010), or country -specific. Siddiqui found (2010) that a particular fusion gene was found in Pakistan, Myanmar and Sudan, at a much lower rate than rep...
متن کاملIndoor radon and childhood leukaemia.
This paper summarises the epidemiological literature on domestic exposure to radon and risk for childhood leukaemia. The results of 12 ecological studies show a consistent pattern of higher incidence and mortality rates for childhood leukaemia in areas with higher average indoor radon concentrations. Although the results of such studies are useful to generate hypotheses, they must be interprete...
متن کاملCataracts in childhood leukaemia.
The incidence and severity of cataract were studied in 37 children who had completed treatment for acute lymphoblastic leukaemia. Twelve (32%) had posterior subcapsular lens opacities. Treatment had included corticosteroids and cranial irradiation, but no dose relationship was evident. The boys were more severely affected than the girls. Although none of the lens opacities was optically signifi...
متن کاملMonocytic leukaemia in childhood.
In 1913 Reschad and Schilling Torgau suggested the possibility of a distinctive hyperplasia affecting the monocytic cells of the blood under the name of ' splenocytic leukaemia.' With the more accurate title of ' monocytic leukaemia,' this is now an established entity. Though still regarded as a rare disease, this condition is being increasingly recognized. In 1933 only twenty histologically au...
متن کاملIonising radiation and risk of death from leukaemia and lymphoma in radiation-monitored workers (INWORKS): an international cohort study
BACKGROUND There is much uncertainty about the risks of leukaemia and lymphoma after repeated or protracted low-dose radiation exposure typical of occupational, environmental, and diagnostic medical settings. We quantified associations between protracted low-dose radiation exposures and leukaemia, lymphoma, and multiple myeloma mortality among radiation-monitored adults employed in France, the ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1991
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.302.6781.907